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Inhibition of pyruvate dehydrogenase kinase 4 ameliorates kidney ischemia-reperfusion injury by reducing succinate accumulation during ischemia and preserving mitochondrial function during reperfusion

Reductive StressBiochemistryMitochondrial FunctionReperfusion InjuryMitochondrial DynamicPhysiologyIschemia-reperfusion InjurySuccinate AccumulationMetabolismMedicineCell BiologyRedox BiologyNephrologyOxidative Stress