Alpha-lipoic acid modulates the diabetes mellitus-mediated neuropathic pain via inhibition of the TRPV1 channel, apoptosis, and oxidative stress in rats

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

The capsaicin receptor: a heat-activated ion channel in the pain pathway

Michael J. Caterina, Mark Schumacher, Makoto Tominaga et al. · Nature · 1997 · 9.1K citations

Life Sciences, Neurobiology, Pharmacology +16

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

Elisabetta Polazzi, Ilaria Mengoni, Marco Caprini et al. · Neurosignals · 2012 · 9K citations · Full text

Life Sciences, Neurobiology, Neuroscience +11

Anti-obesity effects of α-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase

Min‐Seon Kim, Joong‐Yeol Park, Cherl NamKoong et al. · Nature Medicine · 2004 · 520 citations

Life Sciences, Biochemistry, Endocrinology +16

The Sensory Symptoms of Diabetic Polyneuropathy Are Improved With α-Lipoic Acid

Alexei Barinov, P. James B. Dyck, Róbert Hermann et al. · Diabetes Care · 2003 · 355 citations

Medicine, Neurology, Pharmacology +17