Concepedia

<scp>YAP</scp>/<scp>WNT5A</scp>/<scp>FZD4</scp> axis regulates osteogenic differentiation of human periodontal ligament cells under cyclic stretch

Xiaocen Zhang, Maolin Chang, Beike Wang, Xiaoyu Liu, Zhen Zhang, Guangli Han

Journal of Periodontal Research · 2023 · 15 citations · 48 references

DOI

Abstract

WNT5A/FZD4 could be positively regulated by YAP and the YAP/WNT5A/FZD4 axis mediated osteogenic differentiation of hPDLCs under cyclic stretch. This study provided further insight into the biological mechanism of orthodontic tooth movement.

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