NEK2 overexpression aggravates IL-22-induced keratinocyte proliferation and cytokine level increases and IMQ-induced psoriasis-like dermatitis

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Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

Yan Zheng, Dimitry M. Danilenko, Patricia Valdez et al. · Nature · 2006 · 1.8K citations

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Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

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IL‐22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis

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IL-22 Inhibits Epidermal Differentiation and Induces Proinflammatory Gene Expression and Migration of Human Keratinocytes

Katia Boniface, François‐Xavier Bernard, Martine Garcia et al. · The Journal of Immunology · 2005 · 841 citations · Full text

Life Sciences, Dermatology, Immunology +17