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Scribble mis-localization induces adaptive resistance to KRAS G12C inhibitors through feedback activation of MAPK signaling mediated by YAP-induced MRAS

Yap-induced MrasSignal TransductionSignaling PathwayG Protein-coupled ReceptorMedicineReceptor Tyrosine KinaseFeedback ActivationKras G12c InhibitorsPharmacologyCell BiologyCell SignalingProtein Phosphorylation