Concepedia

MACC1 and Gasdermin-E (GSDME) regulate the resistance of colorectal cancer cells to irinotecan

Mingzhen Cheng, Bobo Yang, Zetao Zhan, Simin Lin, Zheping Fang, Yi Gao, Weijie Zhou

Biochemical and Biophysical Research Communications · 2023 · 11 citations · 29 references

DOI

Concepts

References

29

Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer

Herbert I. Hurwitz, Louis Fehrenbacher, William Novotny et al. · New England Journal of Medicine · 2004 · 11K citations · Full text

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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature · 2015 · 6.5K citations

, , +14

Colorectal cancer statistics, 2020

Rebecca L. Siegel, Kimberly D. Miller, Ann Goding Sauer et al. · CA A Cancer Journal for Clinicians · 2020 · 5.1K citations · Full text

, , +16

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Donald W. Nicholson, Ambereen Ali, Nancy A. Thornberry et al. · Nature · 1995 · 4K citations

, , +13

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

Yupeng Wang, Wenqing Gao, Xuyan Shi et al. · Nature · 2017 · 3.2K citations

, , +13