Concepedia

Platelet Transfusion before CVC Placement in Patients with Thrombocytopenia

Floor L. F. van Baarle, Emma K. van de Weerdt, Walter J. F. M. van der Velden, Pieter R. Tuinman, Paula F. Ypma, Walter M. van den Bergh, Astrid Demandt, Emile D. Kerver, A.J. Gerard Jansen, Peter E. Westerweel,

New England Journal of Medicine · 2023 · 71 citations · 25 references

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Abstract

The withholding of prophylactic platelet transfusion before CVC placement in patients with a platelet count of 10,000 to 50,000 per cubic millimeter did not meet the predefined margin for noninferiority and resulted in more CVC-related bleeding events than prophylactic platelet transfusion. (Funded by ZonMw; PACER Dutch Trial Register number, NL5534.).

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