Concepedia

Lewis acid catalyzed spiro annulation of (<i>Z</i>)-3-amino-acrylates with 2-amino arylbenzamides: one-pot synthesis of pyrrole–quinazoline hybrids

Anil Kumar Soda, Krishna Prasad Chinthapally, Phani Krishna C. S., Sai Krishna Chilaka, Sridhar Madabhushi

RSC Advances · 2023 · 10 citations · 45 references

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Concepts

Abstract

Lewis acid promoted spiro annulation for the one-pot synthesis of novel pyrrole–quinazoline hybrid molecules as described.

References

45

6-Alkylamino- and 2,3-Dihydro-3‘-methoxy-2-phenyl-4-quinazolinones and Related Compounds:  Their Synthesis, Cytotoxicity, and Inhibition of Tubulin Polymerization

Mann‐Jen Hour, Li‐Jiau Huang, Sheng‐Chu Kuo et al. · Journal of Medicinal Chemistry · 2000 · 407 citations · Full text

, , +10

Pd-Catalyzed Benzylic C–H Amidation with Benzyl Alcohols in Water: A Strategy To Construct Quinazolinones

Hidemasa Hikawa, Yukari Ino, Hideharu Suzuki et al. · The Journal of Organic Chemistry · 2012 · 213 citations

, , +11

Asymmetric Synthesis of 2,3-Dihydro-2-arylquinazolin-4-ones: Methodology and Application to a Potent Fluorescent Tubulin Inhibitor with Anticancer Activity

Gary M. Chinigo, Mikell Paige, Scott Grindrod et al. · Journal of Medicinal Chemistry · 2008 · 206 citations · Full text

, , +14

Direct One-Pot Synthesis of Luotonin F and Analogues via Rational Logical Design

Yanping Zhu, Zhuan Fei, Mei‐Cai Liu et al. · Organic Letters · 2012 · 143 citations

, , +13

Bismuth Triflate-Catalyzed Three-Component Mannich-Type Reaction

Thierry Ollevier, Étienne Nadeau · The Journal of Organic Chemistry · 2004 · 143 citations

, , +2