Concepedia

Publication | Open Access

A novel EGFR inhibitor, HNPMI, regulates apoptosis and oncogenesis by modulating BCL‐2/BAX and p53 in colon cancer

DOIFull Paper Access

19

Citations

48

References

2023

Year

Jeyalakshmi Kandhavelu, Kumar Subramanian, Vivash Naidoo, Giulia Sebastianelli, Phuong L. Doan, Konda Mani Saravanan, Hande Yapışlar, Ebru Hacıosmanoğlu, Leman Arslan, Samed Ozer,
British Journal of Pharmacology

Abstract

HNPMI is a promising EGFR inhibitor for clinical translation. HNPMI regulated apoptosis and oncogenesis by modulating BCL-2/BAX and p53 in CRC cell lines, showing potential as a therapeutic agent in the treatment of CRC.

References

YearCitations

Page 1