Enhancing the dissolution and bacteriostatic activity of trimethoprim through salt formation

Xingchen Hu, Yuntian Xiao, Luguang Qi, Yunhe Bai, Ying Sun, Yang Ye, Chuang Xie

CrystEngComm · 2023 · 11 citations · 45 references

Concepts

Abstract

Trimethoprim (TMP) is a commonly used BCS class II antibiotic, the water solubility of which needs to be improved to overcome the limitations in oral administration.

References

45