Theranostics · 2023 · 24 citations · 35 references
Life SciencesBiochemistryMolecular BiologyApoptosisCell SignalingSignal TransductionBiomarkers Of Liver InjuryEndoplasmic Reticulum Stress-induced ApoptosisHepatic PathophysiologyLiver DiseaseLiver PhysiologyThioredoxin SystemHepatic ApoptosisHepatocellular Injury MechanismsLiver Gene Expression ResponsesRegulation By E3 Ubiquitin LigasesStress-responsive EnzymesStress-responsive Gene ExpressionStress-responsive RegulationThioredoxin Interacting Protein
Our study revealed a pathogenic role of hepatic TXNIP in NASH and identified a novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of NASH.
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AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1
Ning Wu, Bin Zheng, Adam J. Shaywitz et al. · Molecular Cell · 2013 · 670 citations · Full text
The Interaction of Thioredoxin with Txnip
Parth Patwari, Luke Higgins, William A. Chutkow et al. · Journal of Biological Chemistry · 2006 · 315 citations · Full text
Thioredoxin-interacting protein regulates insulin transcription through microRNA-204
Guanlan Xu, Junqin Chen, Jing Gu et al. · Nature Medicine · 2013 · 282 citations · Full text
Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization
William J. Sullivan, Peter Mullen, E. Schmid et al. · Cell · 2018 · 269 citations · Full text