Concepedia

Nanoengineering multifunctional extracellular vesicles availably mitigate bone loss in osteoporosis through binding to RANKL and rebalancing the Treg/Th17 cells

Zhengyu Yang, Zhen Yang, Lin Ding, Cong Liu, Fujian Zhao, Xiaofeng Chen, Chang Du

Chemical Engineering Journal · 2023 · 14 citations · 21 references

DOI

Concepts

References

21

Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation

David L. Lacey, Emma Timms, Hong‐Lin Tan et al. · Cell · 1998 · 5.5K citations · Full text

, , +13

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

Hisataka Yasuda, Nobuyuki Shima, N. Nakagawa et al. · Proceedings of the National Academy of Sciences · 1998 · 4.3K citations

, , +15

Coupling of bone resorption and formation by RANKL reverse signalling

Yuki Ikebuchi, Shigeki Aoki, Masashi Honma et al. · Nature · 2018 · 554 citations

, , +17

Treg cells suppress osteoclast formation: A new link between the immune system and bone

Mario M. Zaiss, Roland Axmann, Jochen Zwerina et al. · Arthritis & Rheumatism · 2007 · 370 citations

, , +17

Reversal of Osteoporotic Activity by Endothelial Cell-Secreted Bone Targeting and Biocompatible Exosomes

Hongyuan Song, Xiaoqun Li, Zichang Zhao et al. · Nano Letters · 2019 · 309 citations

, , +15