Concepedia

Publication | Open Access

Intracranial injection of natural killer cells engineered with a HER2-targeted chimeric antigen receptor in patients with recurrent glioblastoma

DOIFull Paper Access

105

Citations

34

References

2023

Year

Michael C. Burger, Marie-Thérèse Forster, A Romański, F Straßheimer, Jadranka Macas, Pia S. Zeiner, Eike Steidl, Stefanie Herkt, Katharina J. Weber, Jonathan Schupp,
Neuro-Oncology

Abstract

Intracranial injection of HER2-targeted CAR-NK cells is feasible and safe in patients with recurrent GB. 1 × 108 NK-92/5.28.z cells was determined as the maximum feasible dose for a subsequent expansion cohort with repetitive local injections of CAR-NK cells.

References

YearCitations

Page 1