Repeated blood–brain barrier opening with an implantable ultrasound device for delivery of albumin-bound paclitaxel in patients with recurrent glioblastoma: a phase 1 trial

Phase III Trial of Nanoparticle Albumin-Bound Paclitaxel Compared With Polyethylated Castor Oil–Based Paclitaxel in Women With Breast Cancer

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Blood–brain barrier opening in Alzheimer’s disease using MR-guided focused ultrasound

Nir Lipsman, Ying Meng, Allison Bethune et al. · Nature Communications · 2018 · 941 citations · Full text

Medicine, Neurology, Neuroscience +17

Clinical trial of blood-brain barrier disruption by pulsed ultrasound

Alexandre Carpentier, Michael Canney, Alexandre Vignot et al. · Science Translational Medicine · 2016 · 728 citations

Medicine, Oncology, Radiology +17

Phase I and pharmacokinetic study of ABI-007, a Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel.

Nuhad K. Ibrahim, Neil Desai, Sewa S. Legha et al. · PubMed · 2002 · 630 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study

Todd G. Mainprize, Nir Lipsman, Yuexi Huang et al. · Scientific Reports · 2019 · 605 citations · Full text

Medicine, Oncology, Pharmacology +17