Distinct cAMP Signaling Microdomains Differentially Regulate Melanosomal pH and Pigmentation

Variants of the melanocyte–stimulating hormone receptor gene are associated with red hair and fair skin in humans

Paloma Valverde, Eugene Healy, Ian J. Jackson et al. · Nature Genetics · 1995 · 1K citations

Life Sciences, Dermatology, Genetics +13

Soluble Adenylyl Cyclase as an Evolutionarily Conserved Bicarbonate Sensor

Yanqiu Chen, Martin J. Cann, Tatiana N. Litvin et al. · Science · 2000 · 848 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Central Role of p53 in the Suntan Response and Pathologic Hyperpigmentation

Rutao Cui, Hans R. Widlund, Erez Feige et al. · Cell · 2007 · 634 citations · Full text

Medicine, Dermatology, Oncology +15

Melanocortin 1 Receptor (MC1R) Gene Variants are Associated with an Increased Risk for Cutaneous Melanoma Which is Largely Independent of Skin Type and Hair Color

Cornelis Kennedy, Jeanet ter Huurne, Marjo Berkhout et al. · Journal of Investigative Dermatology · 2001 · 399 citations

Medicine, Dermatology, Genetics +12

Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning

John A. D’Orazio, Tetsuji Nobuhisa, Rutao Cui et al. · Nature · 2006 · 346 citations

Medicine, Dermatology, Pharmacology +16