Concepedia

Heterogeneity of Repolarization and Cell-Cell Variability of Cardiomyocyte Remodeling Within the Myocardial Infarction Border Zone Contribute to Arrhythmia Susceptibility

Matthew Amoni, Dylan Vermoortele, Samaneh Ekhteraei‐Tousi, Rosa Doñate Puertas, Guillaume Gilbert, Mohamad Youness, Bernard Thienpont, Rik Willems, H. Llewelyn Roderick, Piet Claus,

Circulation Arrhythmia and Electrophysiology · 2023 · 23 citations · 50 references

DOIFull text

Open access

Abstract

Heterogeneous cardiomyocyte remodeling in the BZ is driven by uniquely altered gene expression, related to heterogeneity in the local microenvironment, and translates to heterogeneous repolarization and arrhythmia vulnerability in vivo.

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