Multiomics Analyses Reveal Microbiome–Gut–Brain Crosstalk Centered on Aberrant Gamma-Aminobutyric Acid and Tryptophan Metabolism in Drug-Naïve Patients with First-Episode Schizophrenia

Zhuo Wang, Xiuxia Yuan, Zijia Zhu, Lijuan Pang, Shizhi Ding, Xue Li, Yulin Kang, Gangrui Hei, Liyuan Zhang, Xiaoyun Zhang,

Schizophrenia Bulletin · 2023 · 40 citations · 31 references

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Abstract

This study provides new insights into systematic relationships among genes, metabolism, and the gut microbiota that affect brain functional connectivity, thereby affecting SCZ pathogenesis.

References

31