Intravenous Thrombolysis 4.5–9 Hours After Stroke Onset: A Cohort Study from the <scp>TRISP</scp> Collaboration

Abstract

This study showed no evidence in difference of symptomatic intracranial hemorrhage, poor outcome, and mortality in selected stroke patients treated with IVT between >4.5 and 9 hours after stroke onset compared with those treated within 4.5 hours. Advanced neuroimaging for patient selection was associated with lower mortality. ANN NEUROL 2023;94:309-320.