Concepedia

Fucoxanthin protects retinal ganglion cells and promotes parkin-mediated mitophagy against glutamate excitotoxicity

Wei Lian, Xinxin Hu, Juntao Zhang, Yufei Wu, Na Zhao, Haixia Ma, Hengqian He, Qinkang Lu

Neuroreport · 2023 · 10 citations · 18 references

DOIFull text

Open access

Abstract

Fucoxanthin may exert its neuroprotective effect on RGCs via promoting parkin-mediated mitophagy under glutamate excitotoxicity. The neuroprotective effect of fucoxanthin in glaucomatous neurodegeneration and ocular diseases characterized by impaired mitophagy warrants further investigation.

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