Concepedia

DTSEA: A network-based drug target set enrichment analysis method for drug repurposing against COVID-19

Yinchun Su, Jiashuo Wu, Xiangmei Li, Ji Li, Xilong Zhao, Bingyue Pan, Junling Huang, Qingfei Kong, Junwei Han

Computers in Biology and Medicine · 2023 · 14 citations · 42 references

Open access

Concepts

Life SciencesBioinformaticsPharmacologyDrug DiscoveryDrug RepurposingPathway AnalysisComputational Drug DiscoveryComputational Drug RepurposingDisease Network BiologyDrug-target Interaction NetworksGene Set Enrichment AnalysisNetwork-based RepurposingDrug - Target Network AnalysisDrug-target Network AnalysisDrug-target Network ConstructionEnrichment AnalysisNetwork-based Drug-target Prediction

References

42

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 56.7K citations · Full text

Life Sciences, Bioinformatics, Oncology +12

An introduction to ROC analysis

Tom Fawcett · Pattern Recognition Letters · 2005 · 21.3K citations

Computing, Biostatistics, Computer Science +5

The control of the false discovery rate in multiple testing under dependency

Yoav Benjamini, Daniel Yekutieli · The Annals of Statistics · 2001 · 10.8K citations · Full text

Public Health, Biostatistics, A/b Testing +14

DrugBank 5.0: a major update to the DrugBank database for 2018

David S. Wishart, Yannick Djoumbou-Feunang, An Chi Guo et al. · Nucleic Acids Research · 2017 · 8.8K citations · Full text

Medicine, Pharmacology, Drug Information +13

Remdesivir for the Treatment of Covid-19 — Final Report

John H. Beigel, Kay M Tomashek, Lori E. Dodd et al. · New England Journal of Medicine · 2020 · 7.7K citations · Full text

Pharmacy, Infectious Diseases, Pharmacotherapy +15