Network pharmacology-based prediction and validation of the active ingredients and potential mechanisms of the Huangxiong formula for treating ischemic stroke

Reversible middle cerebral artery occlusion without craniectomy in rats.

Enrique Zea Longa, Philip R. Weinstein, Shaun W. Carlson et al. · Stroke · 1989 · 7.4K citations · Full text

Mca Occlusion, Cerebral Vascular Regulation, Neurovascular Disease +18

Janus Kinase Inhibition Ameliorates Ischemic Stroke Injury and Neuroinflammation Through Reducing NLRP3 Inflammasome Activation via JAK2/STAT3 Pathway Inhibition

Hua Zhu, Zhihong Jian, Yi Zhong et al. · Frontiers in Immunology · 2021 · 321 citations · Full text

Target Identification Using Drug Affinity Responsive Target Stability (DARTS)

Brett Lomenick, Gwanghyun Jung, James A. Wohlschlegel et al. · Current Protocols in Chemical Biology · 2011 · 222 citations

Molecular Docking, Protein Targets, Drug Target +15

m6A methylated EphA2 and VEGFA through IGF2BP2/3 regulation promotes vasculogenic mimicry in colorectal cancer via PI3K/AKT and ERK1/2 signaling

Xin Liu, Hongjuan He, Fengwei Zhang et al. · Cell Death and Disease · 2022 · 186 citations · Full text

Protection against acute cerebral ischemia/reperfusion injury by QiShenYiQi via neuroinflammatory network mobilization

Yule Wang, Guangxu Xiao, Shuang He et al. · Biomedicine & Pharmacotherapy · 2020 · 109 citations · Full text

Social Sciences, Oxidative Stress, Neuroinflammation +22