Concepedia

Does polygenic risk for substance‐related traits predict ages of onset and progression of symptoms?

Henry R. Kranzler, Richard Feinn, Heng Xu, Brendan L. Ho, Divya Saini, Olivia R. Nicastro, Anya Jacoby, Sylvanus Toikumo, Joel Gelernter, Emily E. Hartwell,

Addiction · 2023 · 13 citations · 35 references

DOIFull text

Open access

Abstract

Genetic risk for SUDs appears to predict substance use milestones and symptom progression among European-ancestry individuals and, to a lesser extent, African-ancestry individuals.

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