<i>comCDE</i> (Competence) Operon Is Regulated by CcpA in Streptococcus pneumoniae D39

Abstract

Streptococcus pneumoniae is a major cause of bacterial infections in humans, such as pneumonia, bacteremia, meningitis, otitis media, and sinusitis. Like most streptococci, S. pneumoniae is naturally competent and employs this ability to augment its adaptive evolution.