Characterization of the Sterol 24-C-Methyltransferase Genes Reveals a Network of Alternative Sterol Biosynthetic Pathways in <i>Mucor lusitanicus</i>

Kitti Bauer, Bence Rafael, Bernadett Vágó, Sándor Kiss-Vetráb, Anna Molnár, Csilla Szebenyi, Mónika Varga, András Szekeres, Csaba Vágvölgyi, Tamás Papp,

Microbiology Spectrum · 2023 · 13 citations · 44 references

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Abstract

The fungal membrane contains ergosterol instead of cholesterol, which offers a specific point of attack for the defense against pathogenic fungi. Indeed, most antifungal agents target ergosterol or its biosynthesis.

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