Microbiology Spectrum · 2023 · 13 citations · 44 references
Life SciencesMicrobiologyMolecular BiologyEnzymologyMicrobial GeneticsMycologyAntifungal AgentsAntifungal ResistanceAntifungal TherapyFungal GeneticsFungal PathogenesisSterol MetabolismAlternative Steroid Biosynthetic PathwaysAntifungal Resistance MechanismsAzole ResistanceErgosterol Biosynthesis AlterationsFungal Cell MembraneFungal Membrane LipidsFungal Sterol BiosynthesisMucormycosis Treatment
The fungal membrane contains ergosterol instead of cholesterol, which offers a specific point of attack for the defense against pathogenic fungi. Indeed, most antifungal agents target ergosterol or its biosynthesis.
44
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
PubMed · 1997 · 66.6K citations
MycoCosm portal: gearing up for 1000 fungal genomes
Igor V. Grigoriev, Roman Nikitin, Sajeet Haridas et al. · Nucleic Acids Research · 2013 · 1.6K citations · Full text
David A. Bergin, Emer P. Reeves, J. A. A. Renwick et al. · Infection and Immunity · 2005 · 250 citations · Full text