Concepedia

Cu-catalysed three-component C–H trifluoroalkylation of glycine derivatives: access to diverse CF<sub>3</sub>-containing amino acids

Yadong Li, Dengfu Lu, Yuefa Gong

Organic Chemistry Frontiers · 2023 · 16 citations · 59 references

DOI

Concepts

Abstract

A Cu-catalysed and ligand-controlled glycine ligation method is developed for the modular and selective synthesis of diverse CF 3 -containing amino acids and dipeptides.

References

59

Mixed-Ligand Copper(II)-phenolate Complexes:  Effect of Coligand on Enhanced DNA and Protein Binding, DNA Cleavage, and Anticancer Activity

Venugopal Rajendiran, Ramasamy Karthik, Mallayan Palaniandavar et al. · Inorganic Chemistry · 2007 · 585 citations

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Organocatalysis with proline derivatives: improved catalysts for the asymmetric Mannich, nitro-Michael and aldol reactions

Alexander J. A. Cobb, David M. Shaw, Deborah A. Longbottom et al. · Organic & Biomolecular Chemistry · 2004 · 488 citations

, , +6

Copper-Catalyzed C(sp<sup>3</sup>)–C(sp<sup>3</sup>) Bond Formation Using a Hypervalent Iodine Reagent: An Efficient Allylic Trifluoromethylation

Xi Wang, Yuxuan Ye, Songnan Zhang et al. · Journal of the American Chemical Society · 2011 · 460 citations

, , +7

Copper‐Catalyzed Trifluoromethylation of Unactivated Olefins

Andrew T. Parsons, Stephen L. Buchwald · Angewandte Chemie International Edition · 2011 · 415 citations · Full text

, , +9

Redox‐Neutral α‐Allylation of Amines by Combining Palladium Catalysis and Visible‐Light Photoredox Catalysis

Jun Xuan, Tingting Zeng, Zhu‐Jia Feng et al. · Angewandte Chemie International Edition · 2014 · 278 citations

, , +16