Concepedia

Copper-Catalyzed C(sp<sup>3</sup>)–C(sp<sup>3</sup>) Bond Formation Using a Hypervalent Iodine Reagent: An Efficient Allylic Trifluoromethylation

Xi Wang, Yuxuan Ye, Songnan Zhang, Jiajie Feng, Yan Xu, Yan Zhang, Jianbo Wang

Journal of the American Chemical Society · 2011 · 460 citations · 53 references

DOI

Concepts

Abstract

An efficient copper-catalyzed allylic trifluoromethylation reaction has been developed. This reaction provides a general and straightforward way to synthesize allylic trifluoromethylated compounds under mild conditions.

References

53

The Palladium-Catalyzed Trifluoromethylation of Aryl Chlorides

Eun Jin Cho, Todd D. Senecal, Tom Kinzel et al. · Science · 2010 · 779 citations

, , +10

Novel 10‐I‐3 Hypervalent Iodine‐Based Compounds for Electrophilic Trifluoromethylation

Patrick Eisenberger, S. Gischig, Antonio Togni · Chemistry - A European Journal · 2006 · 600 citations

, , +10

Cu-catalyzed cross-dehydrogenative coupling: A versatile strategy for C–C bond formations via the oxidative activation of sp <sup>3</sup> C–H bonds

Zhiping Li, D. Scott Bohle, Chao‐Jun Li · Proceedings of the National Academy of Sciences · 2006 · 592 citations · Full text

, , +14

Pyrrole Synthesis via Allylic sp<sup>3</sup> C−H Activation of Enamines Followed by Intermolecular Coupling with Unactivated Alkynes

Souvik Rakshit, Frédéric W. Patureau, Frank Glorius · Journal of the American Chemical Society · 2010 · 575 citations

, , +13

Strategies for nucleophilic, electrophilic, and radical trifluoromethylations

Jun‐An Ma, Dominique Cahard · Journal of Fluorine Chemistry · 2007 · 560 citations

, , +10