Optimization of β-Lactam Dosing Regimens in Neonatal Infections: Continuous and Extended Administration versus Intermittent Administration

Time to Treatment and Mortality during Mandated Emergency Care for Sepsis

Christopher W. Seymour, Foster Gesten, Hallie C. Prescott et al. · New England Journal of Medicine · 2017 · 2.2K citations · Full text

Veterinary Medicine, Emergency Medical Services, Emergency Medicine +11

Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution

Jason A. Roberts, Carl M. J. Kirkpatrick, Michael S. Roberts et al. · Journal of Antimicrobial Chemotherapy · 2009 · 348 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

New Dutch reference curves for birthweight by gestational age

Gerard H. A. Visser, Paul H.C. Eilers, P.M. Elferink‐Stinkens et al. · Early Human Development · 2009 · 343 citations

Medicine, Obstetrics, Pediatrics +14

Too much of a good thing: a retrospective study of β-lactam concentration–toxicity relationships

Sahand Imani, Hergen Buscher, Debbie Marriott et al. · Journal of Antimicrobial Chemotherapy · 2017 · 308 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Protein binding predictions in infants

Patrick J. McNamara, Jane Alcorn · AAPS PharmSci · 2002 · 202 citations · Full text

Pharmacy, Biochemistry, Pharmacokinetics +16