Concepedia

Cysteine-responsive prodrug of the anti-cancer drug amonafide: fluorogenic adjuvant drug delivery with hydrogen sulfide (H<sub>2</sub>S)

Sulendar K. Mahato, Pallavi Barman, Md. Badirujjaman, Krishna P. Bhabak

Chemical Communications · 2023 · 17 citations · 30 references

DOI

Concepts

Abstract

l -Cysteine (Cys)-responsive turn-on fluorogenic prodrug AM-ITC was developed for the adjuvant delivery of the anti-cancer drug amonafide and the gasotransmitter hydrogen sulfide (H 2 S).

References

30

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Yu Zhao, Hua Wang, Ming Xian · Journal of the American Chemical Society · 2010 · 256 citations

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Reversible Conjugation of Isothiocyanates with Glutathione Catalyzed by Human Glutathione Transferases

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Esterase‐Sensitive Prodrugs with Tunable Release Rates and Direct Generation of Hydrogen Sulfide

Yueqin Zheng, Bingchen Yu, Kaili Ji et al. · Angewandte Chemie International Edition · 2016 · 183 citations

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