Concepedia

Publication | Open Access

Inhibiting efferocytosis reverses macrophage-mediated immunosuppression in the leukemia microenvironment

DOIFull Paper Access

19

Citations

43

References

2023

Year

Joselyn Cruz Cruz, Kristen C. Allison, Lauren S. Page, Alexis J. Jenkins, Xiaodong Wang, H. Shelton Earp, Stephen V. Frye, Douglas K. Graham, Michael R. Verneris, Alisa B. Lee‐Sherick
Frontiers in Immunology

Abstract

These results demonstrate that MerTK inhibition using MRX2843 altered the leukemia microenvironment from tumor-permissive toward immune responsiveness to leukemia and culminated in improved immune-mediated clearance of AML.

References

YearCitations

Page 1