PubMed · 2008 · 96 citations · 10 references
MedicineNephrologyNutritionMicronutrient DeficiencyMineral MetabolismRenal PathophysiologyCalcium DeficiencyCalcium DisordersDisorders Of Calcium MetabolismDisorders Of Phosphate MetabolismMagnesium DeficiencyRenal DiseaseHereditary Hypophosphatemic DisordersMagnesium DisordersMineral Deficiency DisordersMineral Deficiency StatesMineral Deficiency SyndromesMineral Metabolism DisordersRenal Magnesium WastingRenal Phosphate Wasting
Abnormalities of calcium, magnesium and phosphorus are common in hospitalized patients. Infrequently patients might present in the outpatient settings with non-specific symptoms that might be due to abnormalities of divalent cation (magnesium, calcium) or phosphorous metabolism. Several inherited disorders have been identified that result in renal or intestinal wasting of these elements. Physicians need to have a thorough understanding of the mechanism of calcium, magnesium and phosphorous metabolism and diagnoses disorders due to excess or deficiency of these elements. Prompt identification and treatment of the underlying disorders result in prevention of serious morbidity and mortality.
10
Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23
Kenneth E. White, W. Evans, Jeffery L.H. O'Riordan et al. · Nature Genetics · 2000 · 1.5K citations
A practical approach to hypercalcemia.
Mary F. Carroll, David S. Schade · PubMed · 2003 · 260 citations
Medicine, Endocrinology, Surgery +16