An Antifibrotic Breast Implant Surface Coating Significantly Reduces Periprosthetic Capsule Formation

Abstract

Coating of the silicone implant surface with Met-Z2-Y12 alters the periprosthetic capsule architecture and significantly reduces capsule thickness for at least 6 months postoperatively in a murine model. This is a promising step forward in the development of a therapy to prevent capsular contracture.