Transrectal Ultrasound-Guided Transperineal Cryoablation in the Treatment of Prostate Carcinoma: Preliminary Results

Abstract

No AccessJournal of UrologyClinical Urology: Original Article1 Aug 1995Transrectal Ultrasound-Guided Transperineal Cryoablation in the Treatment of Prostate Carcinoma: Preliminary Results J. Wieder, J.D. Schmidt, G. Casola, E. VanSonnenberg, B.F. Stainken, and C.L. Parsons J. WiederJ. Wieder , J.D. SchmidtJ.D. Schmidt , G. CasolaG. Casola , E. VanSonnenbergE. VanSonnenberg , B.F. StainkenB.F. Stainken , and C.L. ParsonsC.L. Parsons View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)67069-1AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We studied ultrasound-guided percutaneous cryoablation for treatment of prostate carcinoma. Materials and Methods: Our series includes 83 individuals who underwent transrectal ultrasound-guided transperineal percutaneous cryoablation of the prostate. Prostate specific antigen levels, biopsy results and complications were assessed at 3 months. Results: Of 61 biopsies 8 (13.1 percent) were positive for carcinoma (half showed stage D disease). Of patients with stages T1 to T3 cancer 92.6 percent were free of disease at 3 months. Prostate specific antigen levels were significantly decreased by an average of 1.90 ng./ml. (p less than 0.05). Major complications were infrequent, including bladder perforation in 1 patient, urethral strictures in 3, bladder outlet obstruction in 2 and partial incontinence in 2. Impotence was frequent but transient. Conclusions: Transrectal ultrasound-guided transperineal percutaneous cryoablation of the prostate produces few major complications and appears at 3 months to be effective in eradicating local prostate tumors. Longer followup is required to test the original hypothesis. References 1 : Cryosurgical treatment of the prostate. Invest. Urol.1966; 3: 372. Google Scholar 2 : Perineal cryosurgery for prostatic carcinoma. J. Urol.1972; 108: 933. 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Google Scholar Division of Urology and Department of Radiology, University of California San Diego Medical Center, San Diego, California.© 1995 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited ByBabaian R, Donnelly B, Bahn D, Baust J, Dineen M, Ellis D, Katz A, Pisters L, Rukstalis D, Shinohara K and Thrasher J (2018) Best Practice Statement on Cryosurgery for the Treatment of Localized Prostate CancerJournal of Urology, VOL. 180, NO. 5, (1993-2004), Online publication date: 1-Nov-2008.GHAFAR M, JOHNSON C, DE LA TAILLE A, BENSON M, BAGIELLA E, FATAL M, OLSSON C and KATZ A (2018) SALVAGE CRYOTHERAPY USING AN ARGON BASED SYSTEM FOR LOCALLY RECURRENT PROSTATE CANCER AFTER RADIATION THERAPY: THE COLUMBIA EXPERIENCEJournal of Urology, VOL. 166, NO. 4, (1333-1338), Online publication date: 1-Oct-2001.MOUL J (2018) PROSTATE SPECIFIC ANTIGEN ONLY PROGRESSION OF PROSTATE CANCERJournal of Urology, VOL. 163, NO. 6, (1632-1642), Online publication date: 1-Jun-2000.PISTERS L, DINNEY C, PETTAWAY C, SCOTT S, BABAIAN R, von ESCHENBACH A and TRONCOSO P (2018) A FEASIBILITY STUDY OF CRYOTHERAPY FOLLOWED BY RADICAL PROSTATECTOMY FOR LOCALLY ADVANCED PROSTATE CANCERJournal of Urology, VOL. 161, NO. 2, (509-514), Online publication date: 1-Feb-1999.SCHMIDT J, PARSONS C and DOYLE J (2018) NEW INDICATIONS FOR RADICAL PROSTATECTOMYJournal of Urology, VOL. 160, NO. 6 Part 2, (2425-2427), Online publication date: 1-Dec-1998.GREENE G, PISTERS L, SCOTT S and VON ESCHENBACH A (2018) PREDICTIVE VALUE OF PROSTATE SPECIFIC ANTIGEN NADIR AFTER SALVAGE CRYOTHERAPYJournal of Urology, VOL. 160, NO. 1, (86-90), Online publication date: 1-Jul-1998.CHIN J, DOWNEY D, MULLIGAN M and FENSTER A (2018) THREE-DIMENSIONAL TRANSRECTAL ULTRASOUND GUIDED CRYOABLATION FOR LOCALIZED PROSTATE CANCER IN NONSURGICAL CANDIDATES: A FEASIBILITY STUDY AND REPORT OF EARLY RESULTSJournal of Urology, VOL. 159, NO. 3, (910-914), Online publication date: 1-Mar-1998.Long J, Fallick M, LaRock D and Rand W (2018) PRELIMINARY OUTCOMES FOLLOWING CRYOSURGICAL ABLATION OF THE PROSTATE IN PATIENTS WITH CLINICALLY LOCALIZED PROSTATE CARCINOMAJournal of Urology, VOL. 159, NO. 2, (477-484), Online publication date: 1-Feb-1998.Pisters L, von Eschenbach A, Scott S, Swanson D, Dinney C, Pettaway C and Babaian R (2018) The Efficacy and Complications of Salvage Cryotherapy of the ProstateJournal of Urology, VOL. 157, NO. 3, (921-925), Online publication date: 1-Mar-1997.Shinohara K, Rhee B, Presti J and Carroll P (2018) CRYOSURGICAL ABLATION OF PROSTATE CANCER: PATTERNS OF CANCER RECURRENCEJournal of Urology, VOL. 158, NO. 6, (2206-2210), Online publication date: 1-Dec-1997.Shinohara K, Connolly J, Presti J and Carroll P (2018) Cryosurgical Treatment of Localized Prostate Cancer (Stages T1 to T4): Preliminary ResultsJournal of Urology, VOL. 156, NO. 1, (115-121), Online publication date: 1-Jul-1996.Pisters L (2018) Editorial: Prostate Cancer–Adjusting the TillerJournal of Urology, VOL. 155, NO. 5, (1678-1680), Online publication date: 1-May-1996. Volume 154Issue 2August 1995Page: 435-441 Advertisement Copyright & Permissions© 1995 by American Urological Association, Inc.MetricsAuthor Information J. Wieder More articles by this author J.D. Schmidt More articles by this author G. Casola More articles by this author E. VanSonnenberg More articles by this author B.F. Stainken More articles by this author C.L. Parsons More articles by this author Expand All Advertisement PDF DownloadLoading ...