Acute IL-6 exposure triggers canonical IL6Ra signaling in hiPSC microglia, but not neural progenitor cells - Concepedia

Concepedia

Publication | Open Access

Acute IL-6 exposure triggers canonical IL6Ra signaling in hiPSC microglia, but not neural progenitor cells

DOI Full Paper Access

25

Citations

81

References

2023

Year

Amalie C. M. Couch, Shiden Solomon, Rodrigo R. R. Duarte, Alessia Marrocu, Yiqing Sun, Laura Sichlinger, Rugilė Matulevičiūtė, Lucia Dutan Polit, Bjørn Hanger, Amelia M. Brown,

Brain Behavior and Immunity

Abstract

Our data provide evidence for cell specific effects of acute IL-6 exposure in a human model system, ultimately suggesting that microglia-NPC co-culture models are required to study how IL-6 influences human cortical neural progenitor cell development in vitro.

References

	Year	Citations

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