Endothelial hyperactivation of mutant MAP3K3 induces cerebral cavernous malformation enhanced by PIK3CA GOF mutation

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Engineering, Biomedical Data Integration, Data Science +11

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

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Functional Genomics, Single Cell Sequencing, Medicine +7

Mutant PIK3CA promotes cell growth and invasion of human cancer cells

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Retro-orbital injections in mice

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Knockout Mouse, Molecular Neuroscience, Medicine +3

Truncating mutations in CCM1, encoding KRIT1, cause hereditary cavernous angiomas

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Genetics, Vascular Malformation, Pathology +3