Estimated Prevalence and Clinical Manifestations of <i>UBA1</i> Variants Associated With VEXAS Syndrome in a Clinical Population

Abstract

This study provides an estimate of the prevalence and a description of the clinical manifestations of UBA1 variants associated with VEXAS syndrome within a single regional health system in the US. Additional studies are needed in unselected and genetically diverse populations to better define general population prevalence and phenotypic spectrum.