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Differential regulation of Ca<sub>v</sub>3.2 and Ca<sub>v</sub>2.2 calcium channels by CB<sub>1</sub> receptors and cannabidiol

35

Citations

60

References

2023

Year

Abstract

Our findings reveal differential modulation of Ca<sub>v</sub> 2.2 and Ca<sub>v</sub> 3.2 channels by CB<sub>1</sub> receptors and CBD. This advances our understanding of how different cannabinoids produce analgesia through action at different voltage-gated calcium channels and could influence the development of novel cannabinoid-based therapeutics for treatment of chronic pain.

References

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