RSC Advances · 2023 · 36 citations · 37 references
EngineeringBioengineeringBiomedical EngineeringBiocompatibilityBiomaterialsTissue EngineeringCell-scaffold InteractionsNerve RegenerationNeural RegenerationRegenerative ScaffoldsScaffold FabricationTissue Engineering ScaffoldsComposite ScaffoldsElectrospun ScaffoldsNanofibrous ScaffoldsNerve Regeneration ScaffoldsPeripheral Myelin Protein ExpressionPeripheral Nerve RegenerationPeripheral Nerve Regeneration ScaffoldsPolycaprolactone Scaffolds
study revealed biocompatibility of the developed scaffolds both with and without an acellular matrix. Gene expression study revealed a significant increase in peripheral myelin protein (PMP22) expression on acellular matrix-coated PCL-MWCNT scaffolds compared to neat PCL counterparts. Overall, the results suggested Schwann cell matrix-coated PCL-MWCNT nanofibers as a promising conduit for peripheral nerve regeneration.
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