Concepedia

Caveolin-1 ameliorates acetaminophen-aggravated inflammatory damage and lipid deposition in non-alcoholic fatty liver disease via the ROS/TXNIP/NLRP3 pathway

Xiangfu Jiang, Yu Li, Dongdong Fu, Tingyu You, Shuai Wu, Xin Jiao, Jiagen Wen, Yan Huang, Chengmu Hu

International Immunopharmacology · 2022 · 28 citations · 29 references

DOI

Concepts

References

29

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

Rongbin Zhou, Aubry Tardivel, Bernard Thorens et al. · Nature Immunology · 2009 · 2.7K citations

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NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

Auvro R. Mridha, Alexander Wree, Avril A. B. Robertson et al. · Journal of Hepatology · 2017 · 1.1K citations · Full text

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NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

Alexander Wree, Akiko Eguchi, Matthew D. McGeough et al. · Hepatology · 2013 · 934 citations · Full text

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Gasdermin D plays a key role as a pyroptosis executor of non-alcoholic steatohepatitis in humans and mice

Bing Xu, Mingzuo Jiang, Yi Chu et al. · Journal of Hepatology · 2017 · 415 citations

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Melatonin alleviates inflammasome‐induced pyroptosis through inhibiting <scp>NF</scp>‐κB/<scp>GSDMD</scp> signal in mice adipose tissue

Zhenjiang Liu, Lu Gan, Yatao Xu et al. · Journal of Pineal Research · 2017 · 371 citations

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