Conditional deletion of Hspa5 leads to spermatogenesis failure and male infertility in mice

Targeted gene disruption of Hsp70-2 results in failed meiosis, germ cell apoptosis, and male infertility.

David J. Dix, James W. Allen, Bianca Collins et al. · Proceedings of the National Academy of Sciences · 1996 · 559 citations

Life Sciences, Cell Biology, Genetics +17

GRP78/BiP Is Required for Cell Proliferation and Protecting the Inner Cell Mass from Apoptosis during Early Mouse Embryonic Development

Shengzhan Luo, Changhui Mao, Brenda Lee et al. · Molecular and Cellular Biology · 2006 · 424 citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +15

Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice

Patricia Sadate-Ngatchou, Christopher J. Payne, Andrea Dearth et al. · genesis · 2008 · 319 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Single-Cell RNA Sequencing of Human, Macaque, and Mouse Testes Uncovers Conserved and Divergent Features of Mammalian Spermatogenesis

Adrienne Niederriter Shami, Xianing Zheng, Sarah K. Munyoki et al. · Developmental Cell · 2020 · 291 citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +15

The Molecular Chaperone Hsp90α Is Required for Meiotic Progression of Spermatocytes beyond Pachytene in the Mouse

Iwona Grad, Christopher R. Cederroth, Joël Walicki et al. · PLoS ONE · 2010 · 171 citations · Full text

Life Sciences, Genetics, Molecular Biology +13