The Journal of Immunology · 1966 · 669 citations · 0 references
Life SciencesBiochemistryImmunologyProtein BiochemistryAntibody CharacterizationAntibody-antigen RecognitionAntibodiesAntigen-antibody InteractionsAntigen-antibody RecognitionGamma Globulin Analysis
Summary Protein A was isolated from S. aureus and shown to precipitate about 45% of a pooled normal human γG preparation. In addition it was demonstrated that protein A reacts with myeloma γG-globulin, H chains from both normal and myeloma γG-globulins and the Fc fragment of normal γG-globulin. Thus, the reaction is not a true antigen-antibody reaction.