Towards a new combination therapy with vectored immunoprophylaxis for HIV: Modeling “shock and kill” strategy

Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission

P. van den Driessche, James Watmough · Mathematical Biosciences · 2002 · 9.9K citations

Veterinary Medicine, Infectious Diseases, Compartmental Modeling +16

Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection

Frank J. Palella, Kathleen M. Delaney, Anne C. Moorman et al. · New England Journal of Medicine · 1998 · 9.5K citations

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Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

Diana Finzi, Joel N. Blankson, Janet D. Siliciano et al. · Nature Medicine · 1999 · 2.1K citations

Life Sciences, Immunology, Infectious Diseases +17

Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells

Janet D. Siliciano, Joleen Kajdas, Diana Finzi et al. · Nature Medicine · 2003 · 1.7K citations

Life Sciences, Immunology, Infectious Diseases +15

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

Nicolas Chomont, Mohamed El‐Far, Petronela Ancuța et al. · Nature Medicine · 2009 · 1.7K citations · Full text

Life Sciences, Immunology, Infectious Diseases +16