Concepedia

Dual functional antioxidant and butyrylcholinesterase inhibitors for the treatment of Alzheimer’s disease: Design, synthesis and evaluation of novel melatonin-alkylbenzylamine hybrids

Peng Liu, Maojun Cheng, Jie Guo, Duanyuan Cao, Jinchong Luo, Yang Wan, Yuanying Fang, Yi Jin, Sai‐Sai Xie, Jing Liu

Bioorganic & Medicinal Chemistry · 2022 · 16 citations · 30 references

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Concepts

References

30

A new and rapid colorimetric determination of acetylcholinesterase activity

George L. Ellman, K. Diane Courtney, Valentino Andres et al. · Biochemical Pharmacology · 1961 · 26.6K citations

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Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

P. Hemachandra Reddy, M. Flint Beal · Trends in Molecular Medicine · 2008 · 942 citations · Full text

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Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer β-amyloid peptide in rodent

Nigel H. Greig, Tadanobu Utsuki, Donald K. Ingram et al. · Proceedings of the National Academy of Sciences · 2005 · 708 citations · Full text

CHANGES IN BRAIN CHOLINESTERASES IN SENILE DEMENTIA OF ALZHEIMER TYPE

Elaine K. Perry, R. H. Perry, G. Blessed et al. · Neuropathology and Applied Neurobiology · 1978 · 550 citations

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Structure-Based Search for New Inhibitors of Cholinesterases

Marek Bajda, Anna Więckowska, Michalina Hebda et al. · International Journal of Molecular Sciences · 2013 · 259 citations · Full text

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