Concepedia

Asymmetric organocatalytic (3 + 2) annulation of propargylic alcohols with indolylnaphthalenols: synergistic construction of axial and central chirality

Yan Xia, Meiwen Liu, Chenxiao Qian, Pengfei Li, Mingxin Dong, Wenjun Li

Organic Chemistry Frontiers · 2022 · 42 citations · 45 references

DOI

Concepts

Abstract

Organocatalytic enantioselective construction of chiral spiro N , N -acetal carbon stereocenters and axially chiral 3-arylindoles has been achieved in one pot.

References

45

Construction of Axially Chiral Compounds via Asymmetric Organocatalysis

Yong‐Bin Wang, Bin Tan · Accounts of Chemical Research · 2018 · 806 citations

, , +9

Organocatalytic Atroposelective Synthesis of Indole Derivatives Bearing Axial Chirality: Strategies and Applications

Hong‐Hao Zhang, Feng Shi · Accounts of Chemical Research · 2022 · 423 citations

, , +12

Organocatalytic asymmetric arylation of indoles enabled by azo groups

Liangwen Qi, Jianhui Mao, Jian Zhang et al. · Nature Chemistry · 2017 · 362 citations

, , +11

Recent Advances in the Catalytic Syntheses of Allenes: A Critical Assessment

Robynne K. Neff, Doug E. Frantz · ACS Catalysis · 2013 · 341 citations

, , +10

Design and Enantioselective Construction of Axially Chiral Naphthyl‐Indole Skeletons

Hong‐Hao Zhang, Cong‐Shuai Wang, Can Li et al. · Angewandte Chemie International Edition · 2016 · 324 citations

, , +17