Pharmaceutical hot melt extrusion process development using QbD and digital twins

Floating hot-melt extruded tablets for gastroretentive controlled drug release system

Mamoru Fukuda, Nicholas A. Peppas, James W. McGinity · Journal of Controlled Release · 2006 · 146 citations

Pharmacy, Pharmaceutics, Controlled Release Formulations +11

Continuous Production of Fenofibrate Solid Lipid Nanoparticles by Hot-Melt Extrusion Technology: a Systematic Study Based on a Quality by Design Approach

Hemlata Patil, Xingyou Ye, Soumyajit Majumdar et al. · The AAPS Journal · 2014 · 125 citations · Full text

Natural Sciences, Materials Engineering, Materials Science +12

Often neglected: PLGA/PLA swelling orchestrates drug release: HME implants

C. Bode, H. Kranz, A. Fivez et al. · Journal of Controlled Release · 2019 · 115 citations · Full text

Engineering, Bioengineering, Biomedical Engineering +8

A novel floating controlled release drug delivery system prepared by hot-melt extrusion

Anh Q. Vo, Joseph T. Morott, Manjeet B. Pimparade et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2015 · 96 citations · Full text

Pharmacy, Pharmaceutics, Controlled Release Formulations +14

Preparation of a solid self-microemulsifying drug delivery system by hot-melt extrusion

Luís Antônio Dantas Silva, Susana Almeida, Ellen Cristine Pineze Alonso et al. · International Journal of Pharmaceutics · 2018 · 83 citations · Full text

Pharmacy, Pharmaceutics, Drug Delivery +16