Scientific Reports · 2022 · 11 citations · 21 references
Veterinary MedicineImmunologyInfectious DiseasesImmunizationVaccine ImmunologyVaccinologyAdaptive Immune ResponsesAdult ImmunizationImmune Response To VaccinationVaccinationVaccine EffectivenessVaccine EfficacyAge-related Vaccine ResponseAge-specific EfficacyAge-specific Vaccine EffectivenessBooster Vaccination TrialsBooster Vaccine ImmunogenicityEfficacy In Older AdultsSerologic Response To Booster VaccinationVaccination In Older Adults
Immune response induced by COVID-19 vaccine booster against delta and omicron variants was assessed in 65 adults (65-84 years old) early aftesr a first booster dose. An increase in SARS-CoV-2 neutralizing antibodies was shown in individuals not previously infected without evidence of an age-related effect, with lower increase in those infected before a single dose of primary vaccination. Of note, humoral response was observed only starting from the 5th day after the boost.
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