Concepedia

Publication | Open Access

Cellular and Molecular Mechanisms of MEK1 Inhibitor–Induced Cardiotoxicity

DOIFull Paper Access

28

Citations

18

References

2022

Year

Tyler Beck, Dimitrios C. Arhontoulis, Jordan Morningstar, Nathaniel Hyams, Andrew Stoddard, Kendra Springs, Rupak Mukherjee, Kristi L. Helke, Lilong Guo, Kelsey Moore,
JACC CardioOncology

Abstract

These data describe pathologic changes observed in trametinib cardiotoxicity, supporting the exploration of drug holidays and alternative pharmacologic strategies for disease prevention.

References

YearCitations

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