Dual role of benzophenone enables a fast and scalable C-4 selective alkylation of pyridines in flow

Jesús Sanjosé‐Orduna, Rodrigo C. Silva, Fabian Raymenants, Bente Reus, Jannik Thaens, Kléber T. de Oliveira, Timothy Noël

Chemical Science · 2022 · 20 citations · 44 references

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Abstract

a HAT mechanism, and by acting as a benign, terminal oxidant. The key role of benzophenone in the operative reaction mechanism has also been revealed through a combination of experimental and computational studies.

References

44