Rh-catalyzed regio-switchable cross-coupling of <i>gem</i>-difluorinated cyclopropanes with allylboronates to structurally diverse fluorinated dienes

Abstract

-difluorinated cyclopropanes and allylboronates. The controlled terminal/internal regioselectivity arises from the fine-tuning of the rhodium catalytic system. Fluorinated 1,3-dienes, 1,4-dienes and 1,5-dienes are therefore produced in good yields with respectively isomerized terminal, internal, and terminal regioselectivity.