Metformin modified chitosan as a multi-functional adjuvant to enhance cisplatin-based tumor chemotherapy efficacy

Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

Jong‐Ho Cha, Wenhao Yang, Weiya Xia et al. · Molecular Cell · 2018 · 732 citations

Medicine, Endoplasmic-reticulum-associated Degradation, Apoptosis +4

DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells

Hiro Sato, Atsuko Niimi, Takaaki Yasuhara et al. · Nature Communications · 2017 · 683 citations · Full text

Tumor Biology, Genome Instability, Cell Regulation +13

Synergistic and low adverse effect cancer immunotherapy by immunogenic chemotherapy and locally expressed PD-L1 trap

Wantong Song, Limei Shen, Ying Wang et al. · Nature Communications · 2018 · 397 citations · Full text

PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy

Xinyi Tu, Bo Qin, Yong Zhang et al. · Molecular Cell · 2019 · 243 citations · Full text

Genome Instability, Molecular Biology, Can Be +7

Inhibition of ATM reverses EMT and decreases metastatic potential of cisplatin-resistant lung cancer cells through JAK/STAT3/PD-L1 pathway

Mingjing Shen, Zhonghua Xu, Weihua Xu et al. · Journal of Experimental & Clinical Cancer Research · 2019 · 212 citations · Full text