Concepedia

Publication | Open Access

Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Promotes Macrophage Activation via LDL Receptor-Independent Mechanisms

DOIFull Paper Access

68

Citations

55

References

2022

Year

Shunsuke Katsuki, Prabhash Kumar Jha, Adrien Lupieri, Toshiaki Nakano, Lívia Silva Araújo Passos, Maximillian A. Rogers, Dakota Becker-Greene, Thanh-Dat Le, Julius L. Decano, Lang Ho Lee,
Circulation Research

Abstract

Circulating PCSK9 induces macrophage activation and vein graft lesion development via LDLR-independent mechanisms. PCSK9 may be a potential target for pharmacologic treatment for this unmet medical need.

References

YearCitations

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